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Anti-JAK2 Mouse mAb [34M56K39]

Purified Mouse Monoclonal Antibody

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货号 规格 价格
M010361
20µL ¥588.00
50µL ¥1080.00
100µL ¥1780.00

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Anti-JAK2 Mouse mAb [34M56K39]
Anti-JAK2 Mouse mAb [34M56K39]
Product NameAnti-JAK2 Mouse mAb
DescriptionPurified Mouse Monoclonal Antibody
Application
  • Applications Legend:
  • WB=Western Blotting
  • IHC-P=Immunohistochemistry (Paraffin)
  • IHC-F=Immunohistochemistry (Frozen)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
IHC-P/IF (Tissue-P), ELISA
DilutionIHC-P 1:50~1:100
ReactivityHuman, Rat, Mouse (Cell)
HostMouse
ClonalityMonoclonal
Clone No.34M56K39
IsotypeIgG1
LabelUnconjugated
ImmunogenSynthetic peptide conjugated to KLH.
FormatBuffer System: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Purification: Affinity Purified.
SynonymsJAK2, Tyrosine-protein kinase JAK2, Janus kinase 2, JAK-2.
Uniprot ID O60674
Gene ID 3717
StorageShipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage.
PrecautionsAnti-JAK2 antibody [34M56K39] is for research use only and not for use in diagnostic or therapeutic procedures.
Background Phosphorylated STATs then form homodimer or heterodimers and translocate to the nucleus to activate gene transcription. For example, cell stimulation with erythropoietin (EPO) during erythropoiesis leads to JAK2 autophosphorylation, activation, and its association with erythropoietin receptor (EPOR) that becomes phosphorylated in its cytoplasmic domain. Then, STAT5 (STAT5A or STAT5B) is recruited, phosphorylated and activated by JAK2.

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