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重组蛋白系列

Recombinant Human Thymosin beta 4

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货号 规格 价格
FL157
10μg ¥198.00
100μg ¥998.00
1mg ¥4080.00

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Product Specifications

Appearance Sterile filtered White lyophilized (freeze-dried) powder.
Purity > 97% by SDS-PAGE or HPLC.
Endotoxin < 0.1 EU/μg of rHuTβ-4 protein as determined by LAL method.
Expression System Expressed in E. coli.
Species Human
Tag Tag free.
Activity Fully biologically active when compared to standard. The biological activity determined by its ability to produce a protective effect against hydrogen peroxide in primary lung fibroblasts is in a concentration range of 0.5-10 μg/ml.
Formulation Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.2.
Reconstitution Before use this product, please read the direction below carefully. This vial must be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in a sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions.
Accession # P62328 Ser2-Ser44
Amino acid sequence SDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES
Molecular weight Approximately 4.9 kDa, a single non-glycosylated polypeptide chain containing 43 amino acids.
Synonyms Fx
Stability & Storage Shipped on wet ice. For long term storage, the product should be stored ≤ -20℃. Please avoid repeated freeze-thaw cycles after reconstitution. 36 months from date of receipt, -20 to -70℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -70℃ under sterile conditions after reconstitution.
Precautions Recombinant Human Thymosin beta 4 is for research use only and not for use in diagnostic or therapeutic procedures.

Background

Thymosin Beta 4 is a naturally occurring peptide encoded by the TMSB4X gene located on Chr. X in humans. It is found in high concentrations in blood platelets, wound fluid and other tissues in the body. Tβ-4 is a major actin regulating peptide and the primary function is to stimulate the productions of T cells, which plays important part of the immune system. The thymosin beta-4 peptide, if used after a heart attack, might reactivate cardiac progenitor cells to repair damaged heart tissue. Recombinant Human Tβ-4 is a 4.9kDa protein containing 44 amino acid residues.

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