| 货号 | 规格 | 价格 |
|---|---|---|
| FL087 | ||
| 5μg | ¥198.00 | |
| 20μg | ¥668.00 | |
| 50μg | ¥1680.00 | |
| 100μg | ¥2980.00 | |
| 250μg | ¥4180.00 | |
| 500μg | ¥8080.00 | |
| 1mg | ¥15300.00 |
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| Appearance | Sterile filtered White lyophilized (freeze-dried) powder. |
|---|---|
| Purity | > 97% by SDS-PAGE or HPLC. |
| Endotoxin | < 0.1 EU/μg of rHuEotaxin-3/CCL26 protein as determined by LAL method. |
| Expression System | Expressed in E. coli. |
| Species | Human |
| Tag | Tag free. |
| Activity | Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human CCR3 transfected HEK293 cells is in a concentration range of 0.5-2.0 μg/ml. |
| Formulation | Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM PB, with 150 mM NaCl, pH 7.4. |
| Reconstitution | Before use this product, please read the direction below carefully. This vial must be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in a sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions. |
| Accession # | Q9Y258 Thr24-Leu94 |
|---|---|
| Amino acid sequence | TRGSDISKTCCFQYSHKPLPWTWVRSYEFTSNSCSQRAVIFTTKRGKKVCTHPRKKWVQKYISLLKTPKQL |
| Molecular weight | Approximately 8.4 kDa, a single non-glycosylated polypeptide chain containing 71 amino acids. |
| Synonyms | CC chemokine IMAC, MIP-4-alpha, Small-inducible cytokine A26, Thymic stroma chemokine-1 (TSC-1) |
| Stability & Storage | Shipped on wet ice. For long term storage, the product should be stored ≤ -20℃. Please avoid repeated freeze-thaw cycles after reconstitution. 12 months from date of receipt, -20 to -70℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -70℃ under sterile conditions after reconstitution. |
| Precautions | Recombinant Human Eotaxin-3/CCL26 is for research use only and not for use in diagnostic or therapeutic procedures. |
| Eotaxin-3 is a CC chemokine that signals through the CCR3 receptor. It is produced by endothelial cells stimulated with IL-4 or IL-13. Eotaxin-3 selectively targets cells expressing CCR3, including eosinophils, basophils, T cells and monocytes. Eotaxin-3 has similar activity to Eotaxin and Eotaxin-2, but the three Eotaxins share only a low degree of sequence homology. CCL26 elicits its effects activity by binding to the cell surface chemokine receptor CCR3, and chemotactic for eosinophils and basophils. Recombinant Human Eotaxin-3 is an 8.4kDa protein containing 71 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. |
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