| 货号 | 规格 | 价格 |
|---|---|---|
| FL057 | ||
| 5μg | ¥198.00 | |
| 20μg | ¥918.00 | |
| 50μg | ¥2280.00 | |
| 100μg | ¥3480.00 | |
| 500μg | ¥8780.00 | |
| 1mg | ¥17600.00 |
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| Appearance | Sterile filtered White lyophilized (freeze-dried) powder. |
|---|---|
| Purity | > 97% by SDS-PAGE or HPLC. |
| Endotoxin | < 0.1 EU/μg of rMuEotaxin/CCL11 protein as determined by LAL method. |
| Expression System | Expressed in E. coli. |
| Species | Mouse |
| Tag | Tag free. |
| Activity | Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using purified eosinophils is in a concentration range of 100-1000 ng/ml. |
| Formulation | Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM PB, with 150 mM NaCl, pH 7.4. |
| Reconstitution | Before use this product, please read the direction below carefully. This vial must be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in a sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions. |
| Accession # | P48298 His24-Pro97 |
|---|---|
| Amino acid sequence | HPGSIPTSCCFIMTSKKIPNTLLKSYKRITNNRCTLKAIVFKTRLGKEICADPKKKWVQDATKHLDQKLQTPKP |
| Molecular weight | Approximately 8.4 kDa, a single non-glycosylated polypeptide chain containing 74 amino acids. |
| Synonyms | Small-inducible Cytokine A11 |
| Stability & Storage | Shipped on wet ice. For long term storage, the product should be stored ≤ -20℃. Please avoid repeated freeze-thaw cycles after reconstitution. 36 months from date of receipt, -20 to -70℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -70℃ under sterile conditions after reconstitution. |
| Precautions | Recombinant Mouse CCL11/Eotaxin is for research use only and not for use in diagnostic or therapeutic procedures. |
| Mouse CCL11 is belonging to the CC chemokine family. CCL11 was first purified from bronchoalveolar lavage fluid of guinea pigs. It was a strong and specific eosinophil chemoattractant in vitro. It can directly chemotactic for eosinophils, but not for monocytes or neutrophils. Mouse CCL11 is approximately 63% identical at the amino acid level to human CCL11. In addition, CCL11 also shows about 60% amino acid sequence identity to human MCPs. CCR3 has been identified to be a specific CCL11 receptor. Recombinant Mouse Eotaxin/CCL11 is an 8.4kDa protein containing 74 amino acid residues. |
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