Purified FITC-conjugated Recombinant Rat Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| F210105 | ||
| 25T | ¥298.00 | |
| 100T | ¥758.00 | |
| 100T×5 | ¥1780.00 |
立即购买
| Product Name | FITC Rat Anti-Mouse CD117 |
|---|---|
| Description | Purified FITC-conjugated Recombinant Rat Monoclonal Antibody |
Application
|
FC |
| Reactivity | Mouse |
| Host | Rat |
| Clonality | Monoclonal |
| Clone No. | 10N59A54 |
| Isotype | IgG2b, κ |
| Label | FITC (Ex/Em: 491/516 nm) |
| Immunogen | Recombinant protein of mouse CD117 |
| Format | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA. |
| Recommended Usage | 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. |
|---|---|
| Synonyms | c-Kit; Sl; Kit; Mast/stem cell growth factor receptor Kit; SCFR; Proto-oncogene c-Kit; Tyrosine-protein kinase Kit; CD117; SCFR; KIT; Mast/stem cell growth factor receptor Kit; Piebald trait protein; Proto-oncogene c-Kit; Tyrosine-protein kinase Kit; p145 c-kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; PBT. |
| Uniprot ID | P05532 |
| Gene ID | 16590 |
| Storage | Shipped on wet ice. Store undiluted between 2℃ and 8℃ and protected from prolonged exposure to light. Do not freeze. |
| Precautions | FITC Rat Anti-Mouse CD117 [10N59A54] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | The c-Kit proto-oncogene is the cellular homolog of the transforming gene of a feline retrovirus (v-Kit). The c-kit protein includes characteristics of a protein kinase transmembrane receptor. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
|---|
| Cellular Location | Isoform 1: Cell membrane ; Single-pass type I membrane protein.Isoform 2: Cell membrane ; Single-pass type I membrane protein. Isoform 3: Cytoplasm. Note: Detected in the cytoplasm of spermatozoa, especially in the equatorial and subacrosomal region of the sperm head. |
|---|
| Tissue Location | Isoform 1 and isoform 2 are detected in bone marrow cells, spermatogonia and spermatocytes, but not in round spermatids, elongating spermatids and spermatozoa. Isoform 3 is detected in round spermatids, elongating spermatids and spermatozoa, but not in spermatogonia and spermatocytes (at protein level). Isoform 1 is widely expressed and detected in fetal liver and bone marrow. Isoform 3 is detected in bone marrow cells enriched in hematopoietic stem cells. |
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