Purified BF488-conjugated Recombinant Rat Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| F209106 | ||
| 25T | ¥848.00 | |
| 100T | ¥1980.00 |
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![BF488 Rat Anti-Mouse CD86 [38K17F97]](https://cdn.epizyme.cn/uploads/products/202608/F209106-1.png?v=20260818140352)
| Product Name | BF488 Rat Anti-Mouse CD86 |
|---|---|
| Description | Purified BF488-conjugated Recombinant Rat Monoclonal Antibody |
Application
|
FC |
| Reactivity | Mouse |
| Host | Rat |
| Clonality | Monoclonal |
| Clone No. | 38K17F97 |
| Isotype | IgG2a, κ |
| Label | BF488 (Ex/Em: 494/517 nm) |
| Immunogen | Recombinant protein of mouse CD86 |
| Format | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA. |
| Recommended Usage | 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. |
|---|---|
| Synonyms | CD86; CD28LG2; T-lymphocyte activation antigen CD86; Activation B7-2 antigen; B70; BU63; CTLA-4 counter-receptor B7.2; FUN-1. |
| Uniprot ID | P42082 |
| Gene ID | 12524 |
| Storage | Shipped on wet ice. Store undiluted between 2℃ and 8℃ and protected from prolonged exposure to light. Do not freeze. |
| Precautions | BF488 Rat Anti-Mouse CD86 [38K17F97] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | Predicted to enable receptor ligand activity. Involved in several processes, including positive regulation of immunoglobulin production; positive regulation of non-canonical NF-kappaB signal transduction; and toll-like receptor 3 signaling pathway. Acts upstream of or within several processes, including cellular response to lipopolysaccharide; positive regulation of T cell proliferation; and toll-like receptor signaling pathway. Located in external side of plasma membrane and intracellular membrane-bounded organelle. Is expressed in central nervous system; mandible; and retina. Used to study Guillain-Barre syndrome. Human ortholog(s) of this gene implicated in several diseases, including IgA vasculitis; autoimmune disease (multiple); chronic lymphocytic leukemia; chronic obstructive pulmonary disease; and systemic scleroderma. Orthologous to human CD86 (CD86 molecule). [provided by Alliance of Genome Resources, Apr 2025] |
|---|
| Cellular Location | Cell membrane; Single-pass type I membrane protein. |
|---|
| Tissue Location | Expressed on the surfaces of antigen-presenting cells. |
|---|
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