Purified RF647-conjugated Recombinant Mouse Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| F107016 | ||
| 25T | ¥638.00 | |
| 100T | ¥1580.00 |
立即购买
![RF647 Mouse Anti-Human TNF-α [67B74P03]](https://cdn.epizyme.cn/uploads/products/202606/F107016-1.png?v=20260617092710)
| Product Name | RF647 Mouse Anti-Human TNF-α |
|---|---|
| Description | Purified RF647-conjugated Recombinant Mouse Monoclonal Antibody |
Application
|
FC |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 67B74P03 |
| Isotype | IgG1, κ |
| Label | RF647 (Ex/Em: 650/671 nm) |
| Immunogen | Recombinant protein of human TNF-α |
| Format | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA. |
| Recommended Usage | 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. |
|---|---|
| Synonyms | TNFA; TNFSF2; TNF; Tumor necrosis factor; Cachectin; TNF-alpha; Tumor necrosis factor ligand superfamily member 2; TNF-a. |
| Uniprot ID | P01375 |
| Gene ID | 7124 |
| Storage | Shipped on wet ice. Store undiluted between 2℃ and 8℃ and protected from prolonged exposure to light. Do not freeze. |
| Precautions | RF647 Mouse Anti-Human TNF-α [67B74P03] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, psoriasis, rheumatoid arthritis ankylosing spondylitis, tuberculosis, autosomal dominant polycystic kidney disease, and cancer. Mutations in this gene affect susceptibility to cerebral malaria, septic shock, and Alzheimer disease. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Aug 2020] |
|---|
| Cellular Location | Cell membrane; Single-pass type II membrane protein. Tumor necrosis factor, membrane form: Membrane ; Single-pass type II membrane protein. Tumor necrosis factor, soluble form: Secreted. C-domain 1: Secreted. C-domain 2: Secreted. |
|---|
| Tissue Location | Bgee: Expressed in granulocyte and 90 other cell types or tissues. ExpressionAtlas: baseline and differential. HPA: Tissue enhanced (bone marrow, lymphoid tissue) |
|---|
总篇数：加载中...
总影响因子：加载中...
最高影响因子：加载中...
上海市闵行区新骏环路760号1号楼3层
400-058-8030
技术支持(电话/微信)：
张老师 18217238522
罗老师 15021027255
李老师 18301721288
如有任何关于雅酶产品问题
欢迎来信咨询
雅酶微信公众号
Copyright © 2023上海雅酶生物医药科技有限公司（Epizyme Biotech）
沪ICP备2021002422号
