Purified APC-conjugated Recombinant Mouse Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| F105615 | ||
| 25T | ¥988.00 | |
| 100T | ¥2480.00 |
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![APC Mouse Anti-Human TIGIT [86S85J66]](https://cdn.epizyme.cn/uploads/products/202606/F105615-1.png?v=20260617092708)
| Product Name | APC Mouse Anti-Human TIGIT |
|---|---|
| Description | Purified APC-conjugated Recombinant Mouse Monoclonal Antibody |
Application
|
FC |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 86S85J66 |
| Isotype | IgG2a, κ |
| Label | APC (Ex/Em: 651/660 nm) |
| Immunogen | Recombinant protein of human TIGIT |
| Format | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA. |
| Recommended Usage | 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. |
|---|---|
| Synonyms | VSIG9; VSTM3; TIGIT; T-cell immunoreceptor with Ig and ITIM domains; V-set and immunoglobulin domain-containing protein 9; V-set and transmembrane domain-containing protein 3. |
| Uniprot ID | Q495A1 |
| Gene ID | 201633 |
| Storage | Shipped on wet ice. Store undiluted between 2℃ and 8℃ and protected from prolonged exposure to light. Do not freeze. |
| Precautions | APC Mouse Anti-Human TIGIT [86S85J66] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.[provided by RefSeq, Sep 2009] |
|---|
| Cellular Location | Cell membrane ; Single-pass type I membrane protein. Note: Clustered to the immunological synapse where it disrupts granule polarization and cytotoxicity of NK cells once engaged with PVR. |
|---|
| Tissue Location | Expressed at low levels on peripheral memory and regulatory CD4+ T-cells and NK cells and is up-regulated following activation of these cells (at protein level). |
|---|
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