Purified BF488-conjugated Recombinant Mouse Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| F102206 | ||
| 25T | ¥638.00 | |
| 100T | ¥1580.00 |
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![BF488 Mouse Anti-Human CD45RO [23J73I76]](https://files.epizyme.cn:5005/uploads/products/202602/F102206-1.png)
| Product Name | BF488 Mouse Anti-Human CD45RO |
|---|---|
| Description | Purified BF488-conjugated Recombinant Mouse Monoclonal Antibody |
Application
|
FC |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 23J73I76 |
| Isotype | IgG2a, κ |
| Label | BF488 |
| Format | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA. |
| Recommended Usage | 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. |
|---|---|
| Synonyms | B220; CD45; CD45R; GP180; IMD105; L-CA; LCA; LY5; T200; Ly-5; Lyt-4; loc; RT7; PTPRC_HUMAN; PTPRC; Leukocyte common antigen (L-CA); 3.1.3.48; Lymphocyte antigen 5 (Ly-5); receptor-type tyrosine-protein phosphatase C. |
| Uniprot ID | P08575 |
| Gene ID | 5788 |
| Storage | Shipped on wet ice. Store undiluted between 2℃ and 8℃ and protected from prolonged exposure to light. Do not freeze. |
| Precautions | BF488 Mouse Anti-Human CD45RO [23J73I76] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | CD45RO is a 180 kD single chain membrane glycoprotein. It is a splice variant of tyrosine phosphatase CD45, lacking the A, B, and C determinants. The CD45RO isoform is expressed on activated and memory T cells, some B cell subsets, activated monocytes/macrophages, and granulocytes. CD45RO enhances both T cell receptor and B cell receptor signaling mediated activation. CD45 and its isoforms non-covalently associate with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1 and CD22. CD45 isoform expression can change in response to cytokines. |
|---|
| Cellular Location | Cell membrane; Single-pass type I membrane protein Membrane raft Synapse Note: Colocalized with DPP4 in membrane rafts. |
|---|
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