Purified PE-conjugated Recombinant Mouse Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| F101208 | ||
| 25T | ¥938.00 | |
| 100T | ¥2080.00 |
立即购买
| Product Name | PE Mouse Anti-Human CD127 |
|---|---|
| Description | Purified PE-conjugated Recombinant Mouse Monoclonal Antibody |
Application
|
FC |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 68C65P27 |
| Isotype | IgG |
| Label | PE |
| Immunogen | Recombinant protein of human CD127 |
| Format | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA. |
| Synonyms | CD 127, CD127, CD127 antigen, CDw127, IL 7R alpha, IL 7R, IL-7 receptor subunit alpha, IL-7R subunit alpha, IL-7R-alpha, IL-7RA, IL7R, IL7RA, IL7RA_HUMAN, IL7Ralpha, ILRA, Interleukin 7 receptor alpha chain, Interleukin 7 receptor, Interleukin 7 receptor isoform H5 6, Interleukin-7 receptor subunit alpha. |
|---|---|
| Uniprot ID | P16871 |
| Gene ID | 3575 |
| Storage | Shipped on wet ice. Store undiluted between 2℃ and 8℃ and protected from prolonged exposure to light. Do not freeze. Stable for 24 months from date of receipt. |
| Precautions | PE Mouse Anti-Human CD127 [68C65P27] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage cells, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be a useful marker for identifying memory and effector T cells. Studies have shown that CD127 expression is down-modulated on Treg cells. It can be used as a marker for differentiation of Treg and conventional T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cell proliferation and development. |
|---|
| Cellular Location | Secreted and Cell membrane. |
|---|
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