Purified PE-conjugated Recombinant Mouse Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| F100508 | ||
| 25T | ¥758.00 | |
| 100T | ¥1680.00 |
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| Product Name | PE Mouse Anti-Human CD16 |
|---|---|
| Description | Purified PE-conjugated Recombinant Mouse Monoclonal Antibody |
Application
|
FC |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 52Q46N54 |
| Isotype | IgG |
| Label | PE |
| Immunogen | Recombinant protein of human CD16 |
| Format | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA. |
| Synonyms | CD 16, CD 16a, CD16, CD16a, CD16a antigen, CD16B, CD16b antigen, Fc fragment of IgG, Fc fragment of IgG low affinity IIIa receptor (CD16), Fc fragment of IgG low affinity IIIa receptor, Fc fragment of IgG receptor IIIa, Fc fragment of IgG, low affinity III, receptor (CD16), Fc fragment of IgG, low affinity IIIa, receptor (CD16), Fc fragment of IgG, low affinity IIIb, receptor (CD16b), Fc gamma R3, Fc gamma receptor III 2 (CD 16), Fc gamma receptor III A, Fc gamma receptor IIIA, Fc gamma receptor IIIb (CD 16), Fc gamma RIII alpha, Fc gamma RIII, Fc gamma RIII beta, Fc gamma RIIIa, Fc gamma RIIIb, Fc of IgG, Fc-gamma receptor III2 (CD 16), Fc-gamma receptor III2 (CD16), Fc-gamma receptor IIIb (CD16), Fc-gamma RIII, Fc-gamma RIII-alpha, Fc-gamma RIIIa, FCG 3, FCG3, FCG3A_HUMAN, FCgammaRIIIA, FCGR 3, FCGR 3A, FCGR3, FCGR3A, FCGR3A protein, FCGRIII, FCGRIII-2, FcR 10, FcR-10, FcR10, FcRIII, FcRIIIa, IGFR 3, IGFR3, IgG Fc receptor III 1, IgG Fc receptor III 2, IgG Fc receptor III-2, IMD20, immunoglobulin G Fc receptor III, immunoglobulin G Fc receptor III-2, Low affinity IIIa receptor, Low affinity immunoglobulin gamma Fc region receptor III A, Low affinity immunoglobulin gamma Fc region receptor III-A, Low affinity immunoglobulin gamma Fc region receptor IIIB, neutrophil-specific antigen NA. |
|---|---|
| Uniprot ID | P08637 |
| Gene ID | 2214 |
| Storage | Shipped on wet ice. Store undiluted between 2℃ and 8℃ and protected from prolonged exposure to light. Do not freeze. Stable for 24 months from date of receipt. |
| Precautions | PE Mouse Anti-Human CD16 [52Q46N54] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | CD16 is known as low affinity IgG receptor III (FcγRIII). It is expressed as two distinct forms (CD16a and CD16b). CD16a (FcγRIIIA) is a 50-65 kD polypeptide-anchored transmembrane protein. It is expressed on the surface of NK cells, activated monocytes, macrophages, and placental trophoblasts in humans. CD16b (FcγRIIIB) is a 48 kD glycosylphosphatidylinositol (GPI)-anchored protein. Its extracellular domain is over 95% homologous to that of CD16a, and it is expressed specifically on neutrophils. CD16 binds aggregated IgG or IgG-antigen complex which functions in NK cell activation, phagocytosis, and antibody-dependent cell-mediated cytotoxicity (ADCC). |
|---|
| Cellular Location | Cell membrane. Secreted. Exists also as a soluble receptor. |
|---|
| Tissue Location | Expressed on natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placental trophoblasts. |
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