Purified RF647-conjugated Recombinant Mouse Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| F100416 | ||
| 25T | ¥638.00 | |
| 100T | ¥1580.00 |
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| Product Name | RF647 Mouse Anti-Human CD14 |
|---|---|
| Description | Purified RF647-conjugated Recombinant Mouse Monoclonal Antibody |
Application
|
FC |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 83F86E77 |
| Isotype | IgG1, κ |
| Label | RF647 |
| Immunogen | Recombinant protein of human CD14 |
| Format | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA. |
| Recommended Usage | 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. |
|---|---|
| Synonyms | CD_antigen=CD14, CD14 antigen, CD14 molecule, CD14_HUMAN, LPS-R, Mo2, Monocyte differentiation antigen CD14, Monocyte differentiation antigen CD14 urinary form, Monocyte differentiation antigen CD14, membrane-bound form, Myeloid cell specific leucine rich glycoprotein, Myeloid cell-specific leucine-rich glycoprotein. |
| Uniprot ID | P08571 |
| Gene ID | 929 |
| Storage | Shipped on wet ice. Store undiluted between 2℃ and 8℃ and protected from prolonged exposure to light. Do not freeze. |
| Precautions | RF647 Mouse Anti-Human CD14 [83F86E77] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide, and to viruses. This gene has been identified as a target candidate in the treatment of SARS-CoV-2-infected patients to potentially lessen or inhibit a severe inflammatory response. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2020] |
|---|
| Cellular Location | Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Membrane raft. Golgi apparatus. Note: Secreted forms may arise by cleavage of the GPI anchor. |
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| Tissue Location | Detected on macrophages (at protein level) (PubMed:1698311). Expressed strongly on the surface of monocytes and weakly on the surface of granulocytes; also expressed by most tissue macrophages. |
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