Purified APC-Cy7-conjugated Recombinant Mouse Monoclonal Antibody
货号 | 规格 | 价格 |
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F100319 | ||
25T | ¥898.00 | |
100T | ¥1980.00 |
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Product Name | APC-Cy7 Mouse Anti-Human CD8 |
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Description | Purified APC-Cy7-conjugated Recombinant Mouse Monoclonal Antibody |
Application
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FC |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Clone No. | 37A35S63 |
Isotype | IgG |
Label | APC-Cy7 |
Immunogen | Recombinant protein of human CD8 |
Format | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA. |
Synonyms | alpha polypeptide (p32), CD_antigen=CD8a, CD8, CD8 antigen alpha polypeptide, CD8 antigen alpha polypeptide (p32), CD8 antigen, alpha polypeptide (p32), CD8a, CD8A antigen, CD8A molecule, CD8A_HUMAN, Leu2, Leu2 T lymphocyte antigen, Ly 2, Ly 35, Ly B, Ly2, Ly3, Ly35, LyB, Lyt 2.1 lymphocyte differentiation antigen (AA at 100), LYT3, MAL, OKT8 T cell antigen, OTTHUMP00000160760, OTTHUMP00000160764, OTTHUMP00000203528, OTTHUMP00000203721, p32, T cell antigen Leu2, T cell co receptor, T lymphocyte differentiation antigen T8/Leu 2, T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein Lyt 2, T-lymphocyte differentiation antigen T8/Leu-2, T8 T cell antigen, T8/Leu-2 T-lymphocyte differentiation antigen. |
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Uniprot ID | P01732 |
Gene ID | 925 |
Storage | Shipped on wet ice. Store undiluted between 2℃ and 8℃ and protected from prolonged exposure to light. Do not freeze. Stable for 24 months from date of receipt. |
Precautions | APC-Cy7 Mouse Anti-Human CD8 [37A35S63] is for research use only and not for use in diagnostic or therapeutic procedures. |
Background | CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation, and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck. |
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Cellular Location | Secreted and Cell membrane. |
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