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Anti-P2Y12 Rabbit mAb [63M57M22]

Purified Recombinant Rabbit Monoclonal Antibody

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货号 规格 价格
R010899
20µL ¥588.00
50µL ¥1080.00
100µL ¥1780.00

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Anti-P2Y12 Rabbit mAb [63M57M22]
Product NameAnti-P2Y12 Rabbit mAb
DescriptionPurified Recombinant Rabbit Monoclonal Antibody
Application
  • Applications Legend:
  • WB=Western Blotting
  • IHC-P=Immunohistochemistry (Paraffin)
  • IHC-F=Immunohistochemistry (Frozen)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, ELISA
DilutionWB 1:1,000~1:2,000
ReactivityHuman
HostRabbit
ClonalityMonoclonal
Clone No.63M57M22
IsotypeIgG
LabelUnconjugated
ImmunogenA synthesized peptide derived from human P2Y12
FormatAffinity purified monoclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
SynonymsADPG-R; BDPLT8; HORK3; P2T(AC); P2Y(12)R; P2Y(AC); P2Y(ADP); P2Y(cyc); P2Y12; SP1999; P2Y12_HUMAN; P2RY12; ADP-glucose receptor (ADPG-R); P2Y12 platelet ADP receptor (P2Y(ADP)).
Molecular weightCalculated MW: 40 kDa; Observed MW: 52 kDa
Uniprot ID Q9H244
Gene ID 64805
StorageShipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage.
PrecautionsAnti-P2Y12 Rabbit mAb [63M57M22] is for research use only and not for use in diagnostic or therapeutic procedures.
Background The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
Cellular Location Cell membrane Multi-pass membrane protein
Tissue Location Highly expressed in the platelets, lower levels in the brain. Lowest levels in the lung, appendix, pituitary and adrenal gland. Expressed in the spinal cord and in the fetal brain.

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