Purified Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R013644 | ||
| 100µL | ¥1780.00 | |
| 50µL | ¥1080.00 | |
| 20µL | ¥588.00 |
| Product Name | Anti-Bax Rabbit mAb |
|---|---|
| Description | Purified Rabbit Monoclonal Antibody |
Application
|
WB, IHC-P, IP, ELISA |
| Dilution | WB 1:500~1:1,000; IHC-P 1:50~1:100; IP 1:20 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 59M52K38 |
| Isotype | IgG |
| Target / Specificity | A synthetic peptide of human Bax |
| Format | Buffer System: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA Purification: Affinity Purified. |
| Gene ID | 581 |
|---|---|
| Other Names | Apoptosis regulator BAX, BAX, Bcl-2-like protein 4, BCL2-associated X protein, Bcl2-L-4, BCL2L4. |
| Calculated MW | Calculated MW: 21 kDa; Observed MW: 21 kDa |
| Primary Accession | Q07812 |
| Storage | Shipped at 4℃. Upon delivery aliquot. Store at 4℃ short term (1~2 weeks). Store at -20℃ for 2 years. Avoid freeze / thaw cycles. |
| Precautions | Anti-Bax antibody [59M52K38] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | Bax is a key component for cellular induced apoptosis through mitochondrial stress. Upon apoptotic stimulation, Bax forms oligomers and translocates from the cytosol to the mitochondrial membrane. Through interactions with pore proteins on the mitochondrial membrane, Bax increases the membrane's permeability, which leads to the release of cytochrome c from mitochondria, activation of caspase-9 and initiation of the caspase activation pathway for apoptosis. |
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