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组织细胞裂解
磷酸酶抑制剂混合液(100×)
产品货号:GRF102
产品规格:1ml
产品价格:298


磷酸酶抑制剂混合(100×)

Phosphatase Inhibitor Cocktail(100×)

本产品冰袋运输;保存于-20保质期12个月。

 

货号规格

goodGRF102(100×,水溶液)  1mL


产品特点

 高效全面——多8种的高效抑制成分,提供比同类产(一般含3~4种抑制剂)更为全面的磷酸酶抑制能力。


产品简介

good本品是一种广谱磷酸酶抑制剂,高效抑制Serine/Threonine Phosphatase,Tyrosine Phosphatase,Acid Phosphatase,Alkaline phosphatase等细胞内所含的磷酸酶。


成分说明

good Sodium fluoride  Sodium orthovanadate  Sodium molybdate  Sodium tartrate Imidazole  Sodium pyrophosphate decahydrate  β-Glycerophosphate  Cantharidin 8种高效磷酸酶抑制剂。


相关论文

good1. Huang, Y., Chen, S., Wu, S., Dong, G., & Sheng, C. (2020). Evodiamine-inspired dual inhibitors of histone deacetylase 1 (HDAC1) and topoisomerase 2 (TOP2) with potent antitumor activity. Acta Pharmaceutica Sinica B, 10(7), 1294-1308. (IF 11.413)
good2. Wang F, Li Z, Zhou J, et al. SIRT1 regulates the phosphorylation and degradation of P27 by deacetylating CDK2 to promote T-cell acute lymphoblastic leukemia progression[J]. Journal of Experimental & Clinical Cancer Research, 2021, 40(1): 1-16.(IF 11.161)
good3. Jiang Z, Wang Y, Li Z, et al. The m6A mRNA demethylase FTO in granulosa cells retards FOS-dependent ovarian aging[J]. Cell death & disease, 2021, 12(8): 1-10.(IF 8.469)
good4. Hua T, Wang H, Fan X, et al. BRD4 Inhibition Attenuates Inflammatory Pain by Ameliorating NLRP3 Inflammasome-Induced Pyroptosis[J]. Frontiers in immunology, 2022, 13: 837977-837977.(IF 7.561)
good5. Zhu Y, Tang X, Xu Y, et al. RNASE2 Mediates Age-Associated B Cell Expansion Through Monocyte Derived IL-10 in Patients With Systemic Lupus Erythematosus[J]. Frontiers in immunology, 2022, 13: 752189-752189.(IF 7.561)
good6. Cheng, J., Li, Y., Wang, X., Dong, G., & Sheng, C. (2020). Discovery of Novel PDEδ Degraders for the Treatment of KRAS Mutant Colorectal Cancer. Journal of Medicinal Chemistry, 63(14), 7892-7905. (IF 7.446)
good7. Pan, C., Chen, L., Wu, R., Shan, H., Zhou, Z., Lin, Y., ... & Wu, C. (2018). Lithium-containing biomaterials inhibit osteoclastogenesis of macrophages in vitro and osteolysis in vivo. Journal of Materials Chemistry B, 6(48), 8115-8126. (IF 6.331)
good8. Xu Z, Shi L, Li D, et al. Real ambient particulate matter-induced lipid metabolism disorder: Roles of peroxisome proliferators-activated receptor alpha[J]. Ecotoxicology and Environmental Safety, 2022, 231: 113173.(IF 6.291)
good9. Pan, C., Shan, H., Wu, T., Liu, W., Lin, Y., Xia, W., ... & Yu, X. (2019). 20 (S)-protopanaxadiol inhibits titanium particle-induced inflammatory osteolysis and RANKL-mediated osteoclastogenesis via MAPK and NF-κB signaling pathways. Frontiers in pharmacology, 9, 1538. (IF 5.810)
good10. GAO, Mengyu, et al. The Role of Nrf2 in the PM-Induced Vascular Injury Under Real Ambient Particulate Matter Exposure in C57/B6 Mice. Frontiers in pharmacology, 2021, 12: 206.(IF 5.810)
good11. Cui, L., Shi, L., Li, D., Li, X., Su, X., Chen, L., ... & Chen, C. (2020). Real-ambient particulate matter exposure-induced cardiotoxicity in C57/B6 mice. Frontiers in Pharmacology, 11, 199. (IF 5.810)
good12. Zhu Y, Tao Z, Chen Y, et al. Exosomal MMP-1 transfers metastasis potential in triple-negative breast cancer through PAR1-mediated EMT[J]. Breast Cancer Research and Treatment, 2022: 1-17.(IF 4.872)
good13. Cai, Y., Li, X., Pan, Z., Zhu, Y., Tuo, J., Meng, Q., ... & Pan, Y. (2020). Anthocyanin ameliorates hypoxia and ischemia induced inflammation and apoptosis by increasing autophagic flux in SH-SY5Y cells. European Journal of Pharmacology, 883, 173360. (IF 4.432)
good14. He Z, Liu X X, Liu X, et al. The role of MEG3 in the proliferation of palatal mesenchymal cells is related to the TGFβ/Smad pathway in TCDD inducing cleft palate[J]. Toxicology and Applied Pharmacology, 2021, 419: 115517.(IF 4.219)
good15. Lv, N., Yuan, J., Ji, A., Shi, L., Gao, M., Cui, L., & Jiang, Q. (2019). Perfluorooctanoic acid-induced toxicities in chicken embryo primary cardiomyocytes: Roles of PPAR alpha and Wnt5a/Frizzled2. Toxicology and applied pharmacology, 381, 114716. (IF 4.219)
good16. Fan, Z., Luo, H., Zhou, J., Wang, F., Zhang, W., Wang, J., ... & Liang, A. (2020). Checkpoint kinase‑1 inhibition and etoposide exhibit a strong synergistic anticancer effect on chronic myeloid leukemia cell line K562 by impairing homologous recombination DNA damage repair. Oncology reports, 44(5), 2152-2164.(IF 3.906)
good17. Huang, D., Xiong, M., Xu, X., Wu, X., Xu, J., Cai, X., ... & Zhou, H. (2020). Bile acids elevated by high-fat feeding induce endoplasmic reticulum stress in intestinal stem cells and contribute to mucosal barrier damage. Biochemical and Biophysical Research Communications, 529(2), 289-295. (IF 3.575)
good18. LIU, Xiaozhuan, et al. The role of lncRNA Meg3 in the proliferation of all-trans retinoic acid-treated mouse embryonic palate mesenchymal cells involves the Smad pathway. Reproductive Toxicology, 2021.(IF 3.143)
good19. Wang Y, Chen X, Yao N, et al. MiR-448 suppresses cell proliferation and glycolysis of hepatocellular carcinoma through inhibiting IGF-1R expression[J]. Journal of Gastrointestinal Oncology, 2022, 13(1): 355.(IF 2.892 )
good20. WU, Hailun, et al. α-Tomatine, a novel early-stage autophagy inhibitor, inhibits autophagy to enhance apoptosis via Beclin-1 in Skov3 cells. Fitoterapia, 2021, 152: 104911.(IF 2.882)


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